Upstream/Midstream Scientist - Purification Media Job at ChromaGenix, Raleigh, NC

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  • ChromaGenix
  • Raleigh, NC

Job Description


ChromaGenix is an innovative start-up providing essential chromatography tools used globally to purify advanced biological therapeutics. As we expand, we are seeking an experienced Upstream/Midstream Scientist to support the development and commercialization of cutting edge purification media which are used globally in the biopharmaceutical industry.

This is a unique opportunity to work onsite in our brand-new facility, where you’ll help lead the production of biological material to enable the effective testing and understanding of key product performance attributes.

Key Responsibilities
· Production and characterization of non GMP feed material from both HEK and CHO lines
· Design and upscale upstream and midstream processes from ml up to 25 liter scales
· Transfer of processes from shake flasks to bioreactors
· Generating robust processes and proceduralize them
· Support product testing and analysis of new products developed at ChromaGenix

Essential Criteria
· Degree in Life Sciences, Biotechnology, or a related field
· Minimum 5 years of experience in upstream roles
· Process experience from transfection to depth filtration
· Analytical experience in relevant techniques including but not limited to Elisa, HPLC, SEC and flow cytometry
· Ability to thrive in a rapid-growth start-up environment


Desirable Criteria
· PhD in Life Sciences, Biotechnology, or a related field
· Downstream purification techniques utilizing FPLCs
· Experience with DoE and statistical analysis
· Working knowledge of ISO9001, ICH and FDA standards and guidelines

Be part of something impactful. Join ChromaGenix in shaping the future of biologics purification on the ground floor of our new manufacturing operation and in one of America’s most exciting life sciences hubs.

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